The brain lacks the lymphatic system to clean up the trash
The brain is an important organ of the human body,
is also the largest energy-consuming organ.
The brain weighs 2-3% of body weight, but
consumes 25% of the body’s energy.
The brain gets nutrients and oxygen through the blood circulatory system,
and also produces a huge amount of metabolic waste.
The brain is different from other organs.
There is no lymphatic circulation system responsible for removing garbage.
Another system is required to clean up the garbage.
Cerebrospinal fluid is often extracted by a “waist-through” method,
for the diagnosis of neurological diseases.
Cerebrospinal fluid finally flows into the liver for detoxification,
to complete the cleanup of the brain’s garbage.
Sleep is the cleanup time of brain waste
Under waking state,
the brain cells are in a busy working state,
The cerebral blood flow is very sufficient,
The whole brain tissue is in an inflated state,
The cerebrospinal fluid “cleaner” cannot enter the scene to clean up the garbage.
Like the industrious sanitation workers in our city,
cleaning the rubbish on city streets only in the dead of night.
When the brain goes to sleep,
blood pressure will decrease and heart rate will slow down.
The cerebral blood flow will decrease.
At this time, the size of the brain will be reduced by about 3-6%.
There are spaces for the “cleaners” of the cerebrospinal fluid to enter the brain tissue to clean up the garbage.
Deep sleep is the best time to clean up the trash
McKenne Nedgod of the University of Rochester, New York, found that
during deep sleep,
Cerebrospinal fluid clean-up garbage starts the high-speed operation mode.
With the pulsating rhythm of deep sleep,
the brain emits 10 to 20 times more garbage.
Nedgod’s second discovery is even more surprising.
The volume of glial cells in the brain miraculously shrunk by 60% during deep sleep,
creating more room for cerebrospinal fluid To remove the garbage.
ß-amyloid is the main component of brain waste
The study found that
the brain is mainly a kind of Called ß-amyloid component.
Scientific research has fully demonstrated that:
ß-amyloid plaque deposited in the brain,
is the main cause of Alzheimer’s disease.
When these ß-amyloid proteins are deposited in different parts of the brain tissue,
will affect the neuronal function of the region,
Different neurological symptoms,
include memory impairment, cognitive impairment,
linguistic dysfunction, spatial visual dysfunction, and
It is worth noting that:
If there is not enough deep sleep,
ß-amyloid will accumulate in the brain,
Influence the brain area that produces deep sleep.
The resulting deep sleep loss,
further prevents the elimination of ß-amyloid in the brain at night,
, resulting in ß-amyloid The accumulation,
forms an endless vicious circle.
ß-amyloid deposition began 20 years ago
Daniel Yaman, MD, famous neuroscience, psychiatry, brain Imaging expert, leader of the world-famous Yaman clinic. He has been engaged in research on brain pathology and brain imaging for many years.
Dr. Yaman has discovered from a large number of clinical cases,
almost all brain tissue of Alzheimer’s disease patients,
discovered 20 years ago There is deposition of ß-amyloid protein,
to detect pathological changes in brain SPECT scans,
and this pathological change can improve sleep,
Adjust for a reasonable diet and moderate exercise.
Deep sleep is hard Reasons
These data pose a prognostic problem:
In your life,
Sleep too little increases the risk of Alzheimer’s The risk of illness.
For people with deep sleep,
This association has been confirmed by many epidemiological studies.
If you have insomnia, sleep apnea
or deep sleep disorder and are not receiving treatment,
you are at higher risk for Alzheimer’s disease .