Unit: Lu Xiangguang (Department of Otolaryngology, Qingdao Eighth People’s Hospital, Qingdao 266100); Wang Qian (Department of Otolaryngology, Qingdao Eighth People’s Hospital, Qingdao 266100); Liu Tao (Qingdao Eighth People’s Hospital) Department of Otorhinolaryngology, Qingdao 266100, China; Han Chao (Department of Otolaryngology, Qingdao Eighth People’s Hospital, Qingdao 266100, China)
Keywords: senile deafness; red blood cell deformability; superoxide dismutase; malondialdehyde [p]
Objective To investigate the relationship between SOD, MDA and erythrocyte deformability in senile deafness, and to provide clinically effective control and delay in the occurrence and development of senile deafness. in accordance with.
Methods Determination of plasma superoxide dismutase (SOD) and lipid peroxidation product malondialdehyde (MDA) levels and blood red blood cell deformability in 68 elderly deaf patients and 50 healthy elderly patients .
Results The level of SOD in elderly patients with deafness decreased, the level of MDA increased, and the deformability of red blood cells decreased. Compared with healthy controls, there was a significant difference (P<0.01), and SOD content and red blood cell deformability. There was a positive correlation (P<0.01), which was negatively correlated with MDA content (P<0.01).
Conclusion The SOD content of patients with senile deafness is decreased, the deformability of red blood cells is decreased, and the level of malondialdehyde (MDA) is increased. It is recommended to increase the SOD content and improve the deformability of red blood cells in patients with senile deafness. , drugs that reduce MDA content.