Ovulation drugs are right and wrong

With the rapid development of society and changes in people’s living environment and living habits, the incidence of infertility is increasing year by year. The incidence of infertility has reached 10-15%. With the increasing importance of women’s social roles, ovulation impaired infertility is increasing.

 The ovulation drug is right and wrong

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ovulation time can be self-tested

First let everyone know about the normal ovulation process. Humans ovulate once every 28 days, and the left and right ovaries alternate. The small follicles grow from the menstrual period, develop into mature follicles after 12 to 14 days, and then discharge the eggs. If they are not refined within 24 hours after ovulation, the eggs will degenerate and disappear.

How do you know your ovulation time? There are several ways:

The ovulation drug is right and wrong

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Calendar method: Women with regular menstrual cycles, ovulation usually occurs about 14 days before the next menstrual period.

Basic body temperature method: The basal body temperature in the normal ovulation menstrual cycle is biphasic, that is, the basal body temperature after ovulation is 0.3-0.5 °C higher than that before ovulation. It is generally considered that the lowest value of basal body temperature or the day before the rise is the ovulation period, and 4 to 5 days before and after this is called the easy pregnancy. However, lack of sleep, physical discomfort and emotional changes can interfere with body temperature measurements. There are also B-mode ultrasound monitoring follicular development and ovulation, reproductive endocrine hormone determination, etc., but these methods need to be carried out under the guidance of a physician.

For patients with irregular menstruation and ovulation disorders, the above methods may not work, and need to the regular assisted reproductive center for treatment.

Treatment of ovulation disorders

What is the cause of ovulation disorders? Here are the following:

The ovulation drug is right and wrong

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Thalamic dysfunction leads to ovulation disorders: such as trauma, hyperkinesia, underweight, and severe systemic wasting disease;

Pituitary ovulatory disorder: pituitary tumor Pituitary destruction, Xi’s syndrome (caused by postpartum hemorrhage, excessive shock time), hyperprolactinemia, etc.;

Ovarian ovulatory disorder: congenital ovary Premature ovarian failure, ovarian functional tumors caused by dysplasia, various causes. Ovarian endometriosis not only destroys ovarian tissue, but also causes severe adhesions and infertility;

polycystic ovary syndrome;

Luteinized unruptured follicular syndrome;

Other: diseases of endocrine metabolism, such as thyroid, adrenal dysfunction, severe diabetes and severe malnutrition Can affect ovarian function leading to infertility.

There are advantages and disadvantages to ovulation drugs

The ovulation drug is right and wrong

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Patient ovulation infertility patients, after diagnosis by doctors, to rule out related diseases and infertility factors such as fallopian tubes, men, and reproductive endocrine hormone levels, it is feasible to promote ovulation treatment. Ovulation-promoting drugs have their side effects at the same time as their mother’s dreams, mainly the complications of ovulation induction, such as ovarian hyperstimulation syndrome, multiple pregnancy, ovarian torsion and so on.

Ovarian hyperstimulation syndrome:

is a human body that overreacts to ovulation-promoting drugs, with bilateral ovarian multifollicular development and ovarian enlargement Abnormal capillary permeability, acute fluid loss and protein loss (extravasation into the third gap, such as the abdominal cavity) is characterized by a series of complications of clinical symptoms. Occasionally occurs in natural pregnancy.

 The ovulation drug is right and wrong

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Its typical symptoms are different degrees of bloating , nausea, vomiting, diarrhea, further developed into drowsiness, fear of eating, difficulty breathing and decreased urine output. Common signs are rapid weight gain, ascites, oliguria or anuria. Concentration of blood, insufficient blood volume, increased white blood cells, electrolyte imbalance, pleural effusion, respiratory distress syndrome, accompanied by thrombotic tendency or vascular embolism. It is more likely to occur in young, low-weight, ovarian polycystic or allergic patients. Patients with severe ovarian hyperstimulation syndrome require hospitalization.

Multiple Pregnancy:

A pregnancy has two or more fetuses called multiple pregnancies. The incidence of multiple pregnancies in human natural pregnancy is about 1:89n-1 (n represents the number of fetuses in a pregnancy, such as twins 1:89). With the use of ovulation-promoting drugs, the incidence of multiple pregnancies has also increased.

 The ovulation drug is right and wrong

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maternal complications in multiple pregnancies and Abortion rate, perinatal morbidity, and mortality increased. Common maternal and child complications include preeclampsia, prenatal anemia, polyhydramnios, miscarriage, premature delivery, postpartum hemorrhage, intrauterine growth retardation, neonatal respiratory distress syndrome, fetal malformation, and increased cesarean section rate. Multiple pregnancies also increase the financial burden on families and society. Standardized ovulation induction can reduce the incidence of multiple pregnancies to some extent. In the event of multiple pregnancies, multiple births can be reduced by reducing the number of pregnancies, reducing the complications of multiple pregnancies and improving maternal and child outcomes. However, the reduction of fetal surgery also has its risks.

Ovarian torsion:

A complication resulting from an enlarged ovary. Occurred in ovarian cysts with a diameter of 5 ~ 6cm, ovarian stimulation after ovulation, ovarian hyperstimulation syndrome. It is manifested as acute abdominal pain. If the ovaries are reversed, you may end up losing one side of the ovaries and pregnancy.

 Ovulation drugs are right and wrong

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Using ovulation drugs Not recommended

For ovulation induction drugs, there are two types of oral and injection drugs, no matter which drug needs to be opened by the doctor according to the patient’s specific conditions, guide medication.>. Ultrasound monitoring of follicular development and endometrial thickness was performed during the course of medication. The doctor will adjust the dosage in a timely manner.

In real life, it is precisely because the ovulation-promoting drugs can cause complications of multiple pregnancies and is used by many illegal traders. Many families use ovulation-promoting drugs through abnormal channels because they are eager to have children or to give birth to twins.

In fact, for people with normal menstruation and normal ovulation, there is no difference in the chances of pregnancy with or without ovulation, and the use of ovulation drugs does increase the chance of multiple pregnancy.>. Although ovulation-promoting drugs alone do not increase the chances of miscarriage, fetal malformations, and neonatal morbidity, the risk of these complications remains.

 The ovulation drug is right and wrong

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We have encountered a polycystic In patients with ovarian syndrome, the main cause of infertility in these patients is sparse ovulation or non-ovulation. She takes ovulation drugs on her own. She thinks she can have ovulation and can go to menstruation normally. In fact, she still has no follicular development. When she came to menstruation, it made her become anxious and panicked and thought she could not get pregnant. I explained her current condition, gave a systematic examination and standardized ovulation treatment, helped her to successfully conceive, and made her happy smile.

I would like to tell you that ovulation-promoting drugs cannot be abused without authorization. Patients with ovulatory infertility need to go to the regular assisted reproductive center for doctor’s standardized diagnosis and treatment. For families who are eager to have twins and are eager to give birth to twins, don’t think about dreams through ovulation-promoting drugs, and use a sentence that is slightly superstitious. “There must be life in the end, and there is no time to ask for it.”

 The ovulation drug is right and wrong

(This article is taken from “The medicine is good: there is no problem with this medicine” , by Li Yining and Wang Xiuxia)