Gout is a chronic disease caused by a disorder of sputum metabolism. The main cause of the disease is overeating, especially the consumption of foods high in sputum. This article focuses on the causes, symptoms, and tests of gout formation. Understanding these can help gout patients better strengthen their care and control their condition.
The cause of gout formation: Gout is mainly caused by abnormal metabolism of sputum in the body, leading to high blood uric acid, which forms uric acid crystals deposited in the patient, making the patient Inflammation, redness, and abnormal pain.
Living factors: There is no regularity in long-term life. It is easy to make the normal rhythm of the human body clock disrupted, increase the acidification of the body, and make the uric acid metabolism in the body unbalanced, leading to gout.
Dietary factors: The diet is not standardized, irregular, and eat too much food with high content of cockroaches, such as seafood, big fish and meat, animal internal organs, etc., so that the uric acid content in the body is too high, leading to uric acid crystallization Deposition in the body.
Environmental factors: The dissolution of general substances is mostly the higher the temperature, the more thorough the dissolution, the same for blood uric acid. When the joint area is in a cold and humid environment for a long time, it will accelerate the deposition of joint uric acid. In addition, cold joints can cause vasospasm to contract, resulting in poor blood circulation, which can cause gout.
Symptoms and signs of gout: Clinically, gout is generally divided into four periods, namely, asymptomatic hyperuricemia, acute gouty arthritis, and intermittent gout attacks. Chronic gouty arthritis may occur in the 2nd to 4th stages. Although gout is divided into 4 stages, it does not mean that every patient with gout will go through these periods in sequence. Patients should undergo regular physical examinations in order to detect problems early.
Asymptomatic period: This stage only shows hyperuricemia. Hyperuricemia (HUA) refers to the high uric acid level higher than 420mol/L in men and higher than 360mol/L in women under normal sputum diet. It can be called hyperuricemia and childhood blood. The mean value of uric acid is 214 mol/L. After puberty, uric acid in male serum begins to increase, while the increase in uric acid concentration in female serum is mainly after menopause. The uric acid concentration in the serum of patients with asymptomatic period increased, but there were no clinical symptoms such as arthritis, tophi or uric acid stones.
Many patients may have hyperuricemia for the rest of their lives without causing gout. Some men develop this symptom during puberty, which may be related to family history of gout, and women often appear during menopause. Asymptomatic hyperuricemia may eventually survive, but may also be converted into acute gouty arthritis or kidney stones. Most patients with asymptomatic hyperuricemia will develop gout symptoms first, and then switch to other situations, but also note that about 10% to 40% of patients will have kidney stones first.
Acute phase: acute arthritis is the main manifestation. The first gout attack in patients with large toe joints, about 60% to 85%, most patients can find predisposing factors, such as excessive diet or local trauma. Symptoms tend to be sudden at the first episode, and 70% of patients have prodromal symptoms such as local discomfort, varicose veins of the lower extremities, headache, insomnia, irritability, bloating, belching, constipation or diarrhea, stomach cramps, etc. . During this period, patients will have severe pain symptoms in the affected joints. In the early stage of the disease, they often invade a single joint (90%). About half of them occur in the joints of the soles of the feet and toes. When the attack occurs, the pain is unbearable and the shoes cannot be put on. After the development, it is likely to invade multiple joints. The gout often includes large toes, insteps, bare feet, heels, knees, wrists, fingers, etc., but other parts will also attack. Therefore, patients should maintain a high degree of alertness, do not think that the pain in other parts must not be caused by gout.
Prevention of gout: For patients with asymptomatic hyperuricemia, prevention of gout attacks is mainly based on non-drug therapy. In order to better prevent gout, you need to do the following 2 points.
Control your weight: Control your weight and prevent gout. Especially for gout patients, in order to avoid gout attacks, the total daily calories should be 10% to 15% lower than normal people. Do not eat too much, too much food per meal, and not eat too much snacks. Exercise more. .
Control : Patients with gout should control the intake of sputum. The daily sputum should be controlled below 150 mg, especially in the 2 to 3 days of acute attack. . In the chronic phase, foods with very low or no sputum content should be used at least 2 days a week, and low-grade meals can be used in the remaining days.