Drug classics and targeted therapy technology
□Gu Zhangsheng Huzhou Hospital of Zhejiang Province
Targeting, as the name suggests, is the action taken on a particular goal. Targeted therapies that are now widely admired in the oncology community have been identified as highly targeted treatments. When a certain drug enters the body, it specifically selects a carcinogenic site to combine the action, so that the tumor cell specifically dies without affecting the normal tissue cells around the tumor, and has the effects of improving the curative effect and reducing the side effects.
Targeted therapy technology for oncology treatment seems to be a common concept in the medical community. In fact, any drug that selectively binds to a site to exert specific efficacy is a targeted therapeutic technique. For example, non-steroidal anti-inflammatory analgesics, which can selectively inhibit cyclooxygenase-2, are more targeted than non-selective anti-inflammatory analgesics produced earlier. Anti-inflammatory analgesics; as in the gamma knife technique, the normal or diseased tissue of the skull is selectively determined as a target by stereotactic orientation, and the gamma ray is used for a large-dose focused irradiation to make a focal Sexual necrosis or functional changes to achieve a cure for disease, but also a targeted treatment technology.
Through the history of Chinese medicine, in fact, the theory and practice of targeted therapy has been widely used. In ancient Chinese medical professions, in the long-term clinical practice, it was clarified that certain drugs have a special selective effect on a meridian meridian, that is, the meridian-related diseases have better therapeutic effects and form the theory of drug return.
The same class of drugs often play different roles because of their different constitutions. Studying the drug’s return can better guide the clinical use of drugs. Such as the dissolving cold medicine in the drug, ephedra, cassia twig, perilla, etc. into the lung, may be used for the treatment of lung-related conditions, and the treatment of lung-related diseases, such as sputum, wind and wind, Not obvious. In addition to entering the lungs, the ephedra also enters the bladder, so it has the effect of benefiting water. In addition to the lungs, the perilla enters the spleen, so there is a role in the wideness of the qi.
The treatment of different syndromes caused by different meridians often uses different drugs. For example, headache, because of different parts, the different meridians of the line can be identified as different lesions, the pain in the forehead is more related to the Yangmingjing; the pain in both sides is more related to Shaoyangjing; Most of the subjects are related to the Sun.
Different meridian diseases require different drug treatments. For example, the sun is selected from the scorpion, and the yangming is selected from the white peony. On this basis, Jin Yuan medical doctor Zhang Jiegu also created the “inducing the report” theory, making a drug a guide to another drug, guiding him to act on the designated meridian, improve the efficacy.
The treatment of diseases by acupoints is an extension of the theory of drug return. “Four total acupoint songs” “The belly is three miles away, the waist is in the middle of the committee, the head item is missing, and the face is close to the valley.” According to the path of the meridians, the pathology of a certain or a certain organ can be followed. Acupuncture or massage treatment is performed on any acupuncture point on the path to achieve therapeutic purposes by adjusting the blood of the meridian. For example, the position of the pregnant woman is not correct, modern medicine often uses the method of knee position to correct, but according to the meridian theory, the Chinese medicine can achieve the same effect through moxibustion to the yin point.
Drug classics and targeted therapy, one ancient and one present, one in one and one west, in fact, the essence is the same, the theoretical basis is the same. (Gu Zhangsheng)