Cancer Genetic Rankings | Different cancers have different genetic risks!

The cancer is inherited, not a hole in the wind. According to records, the Napoleon family, his father, grandfather, three sisters and four brothers, as well as Napoleon himself died of stomach cancer. In the 1860s, a French doctor reported that 15 of the 24 women in his family died of cancer and 10 had breast cancer, and 4 of the 5 children of the second generation died of cancer.

 Cancer Genetic Rankings | Different cancers have different genetic risks!

Although in recent years, cancer has always been medicine Research hotspots have also emerged a number of new drugs and new treatments. However, the fact is that cancer is still difficult to break through. The treatment of cancer is still based on surgery, radiotherapy and chemotherapy. The drugs are still based on traditional drugs such as fluorouracils and platinum. Lord, such as the new generation of oral, high-efficiency chemotherapy drug Viktor® Teggio capsules for the treatment of gastric cancer. Therefore, in this era of “talking about cancer,” people with cancer in their homes often worry that they also have cancer.

About the hereditary nature of cancer, it is medically recognized that cancer has a certain relationship with heredity, but it is not directly transmitted to the next generation. Different tumors have different ways of genetic transmission.

Cancer body does not necessarily have cancer

Cancer Genetic Rankings|Different Cancer Genetic Risks!

As far as the current etiology studies are concerned, the role of genetic factors in most tumorigenesis is the susceptibility or predisposition to carcinogenic factors. In other words, cancer constitution only has some internal factors, whether cancer is formed, but also depends on environmental factors, diet and lifestyle, and external carcinogens.

Classification of tumors closely related to heredity

Medically, tumors closely related to heredity can be divided into two categories: one is a hereditary tumor completely determined by genetics; The other type is that there is no material basis for heredity, but there is a clear genetic predisposition, that is, a cancer with a so-called “cancer quality”.

There are few hereditary tumors, which are common in some children’s tumors. Another type of genetically predisposed tumor, such as familial ring colon polyps, is prone to colon cancer; patients with hereditary immunodeficiency syndrome have low immune function and are prone to lymphatic network tumors such as leukemia and lymphosarcoma.

There are still some cancers. Although no exact genetic evidence is found, their onset sometimes shows familial aggregation. For example, gastric cancer, colorectal cancer, breast cancer, uterine cancer, liver cancer, and lung cancer have so-called “high cancer.” Family report.

 Cancer Genetic Rankings | Different cancers have different genetic risks!

The following cancers have a genetic predisposition:

1, colorectal cancer: familial adenomatous polyps, easy to develop into intestinal cancer, the possibility of children inheriting parents up to 50%, manifested as intergenerational inheritance, pass the male does not pass the female. It is recommended that this group of people undergo colonoscopy 10 years in advance and insist on doing it every year.

2. Breast cancer: The mother or sister has had breast cancer, and the prevalence is 3 times higher than that of the average woman. The heritability of bilateral breast cancer is more obvious. Women with a family history should be examined annually at the age of 30; women with a genetic predisposition should consciously perform a “breast self-test” from the age of 20, especially after menstruation.

3, gastric cancer: diffuse gastric cancer has a genetic predisposition. In a family, at least two of the first or second generation are ill, and one person is younger than 50 years old, and the type is diffuse gastric cancer, which is considered to be hereditary gastric cancer. Children of such patients should pay attention to stay away from risk factors, pay attention to diet, lifestyle, etc., and check regularly.

4, liver cancer: parents with liver cancer, children are primary prevention targets, due to the vertical transmission of hepatitis B virus, easy to cause family aggregation tendency of liver cancer. Mothers carry hepatitis B virus, and their offspring have a higher incidence of liver cancer, and should pay attention to regular physical examination.

5. Lung cancer: Studies have shown that people who have lung cancer and smoke in close relatives are 14 times more likely to develop cancer than the average person. Among patients with lung squamous cell carcinoma, 35.8% had a family history; in women with alveolar cell carcinoma, up to 58.3%. This group of people must strictly quit smoking, pay attention to stay away from risk factors.

Clinically inherited cancer must have cancer

Cancer Genetic Ranking|Different Cancer Genetic Risks!

A high-risk population with a genetic predisposition may not necessarily develop cancer, provided that it raises awareness of cancer prevention, keeps away from carcinogenic factors, and changes inappropriate lifestyles. Regular diet, moderate exercise; maintain an optimistic attitude; stay away from carcinogens; early screening, regular physical examination, these are the key ways to prevent cancer, for people with a family history of cancer and the general population.

 Cancer Genetic Rankings | Different cancers have different genetic risks!